![](https://i0.wp.com/radrounds.com/wp-content/uploads/2021/05/RadswikiAchalasia01.jpeg?resize=593%2C600&ssl=1)
* Failure of the lower esophageal sphincter (LES) to relax.
* Primary achalasia: associated with loss of ganglion cells in the esophageal myenteric plexus.
* Secondary achalasia is relatively uncommon. Etiologies include certain malignancies, diabetes mellitus, and Chagas disease.
Credit: RadsWiki
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