Diagnosis: Peripheral vascular disease. Small vessel disease in lower extremities resulting in tissue loss, gangrene in a non-smoker.

Findings: Images demonstrate significant and extensive small vessel disease. Peripheral vascular disease (PVD) is characterized by the narrowing or blockage of blood vessels in the peripheral arteries, leading to reduced blood flow to the extremities. This can result in tissue damage, ulceration, and, in severe cases, gangrene. While other conditions like venous insufficiency, arterial embolism, and cellulitis can present with similar symptoms, the presence of small vessel disease and gangrene in the lower extremities is most indicative of PVD, especially in a non-smoker.

Credit: Dr. Leonardo Valentin MD (Physician | Image-guided therapy | Sports imaging & MSK interventions | Board Certified Vascular & Interventional Radiologist | Former US REP Nominee. Twitter: @drleovalentin